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Effects of Marijuana on Mental Health: Depression

Highlights
– THC and CBD appear to have antidepressant-like effects in animal models at certain doses but not others.
– Marijuana has been associated with diminished motivation, but a distinct “cannabis amotivational syndrome”
has yet to be substantiated.

Medical cannabis and mental health: A guided systematic review

This review considers the potential influences of the use of cannabis for therapeutic purposes (CTP) on areas of interest to mental health professionals, with foci on adult psychopathology and assessment. We identified 31 articles relating to the use of CTP and mental health, and 29 review articles on cannabis use and mental health that did not focus on use for therapeutic purposes.